Going to cheat by posting two lines, one only because it should be considered one of the most memorable opening lines in gaming, the other because it is the most groan-inducing line I have ever heard in my life:
“The right man in the wrong place can make all the difference in the world.”
"We run, together...like Mario and Princess 'Beach.'"
"But how will the beings of the universe view our resolve? I doubt they will understand what we did...the danger we barely averted. They will hold tribunals and investigations. They will hold us responsible."